Curriculum Vitae Dr. Carmelo García
HONORS
| 1972-1977 | Honor registration at the University of Puerto Rico |
| 1973 | HUC Medal in Chemistry and Physics |
| 1973-1974 | "Who is Who"- Certification |
| 1974 | Magna Cum Laude (Assoc. Degree - Natural Sciences) |
| 1976 | Magna Cum Laude (B.S. Chemistry) |
| 1982 | Magna Cum Laude (Ph.D. Physical Chemistry |
| 1987 | UPR Recognition for Academic Excellence and Productivity |
| 1999 | UPR Recognition for Academic Excellence and Productivity |
DOCTORAL THESIS
| "Photochemical Investigations on Model-Compounds of Epoxy-Resins" (Advisor: Prof. Dr. H.-J. Timpe) |
PhD AND POST. DOC
| TRAINING Photochemistry, Quantum Chemistry and Laser Photomedicine |
LANGUAGES - Spanish, English and German
PROFESSIONAL POSITIONS
| 1979-1980 | Research Assistant for Photochemistry at the TH-"Carl Schorlemmer", Merseburg, DDR |
| 1982-1984 | Post-doctoral Research on Quantum-Chemical Calculations on the butadiene photochemical reaction at the FU-Berlin, West Germany (Under supervision of V.Bonaci…-Kouteckí) |
| 1984-1987 | Assistant Professor at the Department of Chemistry at the Humacao University College, Humacao (PR). |
| 1987-1984 | Associate professor at the Humacao University College (Humacao PR) |
| 1984 to present | Full professor at the Humacao University College |
| 1990-1992 | Visiting Associate Professor at the Harvard Medical School (Boston, MA) |
| 1990 to present | Visiting Chemist at Massachusetts General Hospital (Boston, MA) |
TEACHING EXPERIENCE
| Chemistry 3001-3002 | General Chemistry |
| Chemistry 4041-4042 | Physical Chemistry |
| Chemistry 4051-4052 | Intermediate Lab of Physical Chemistry |
| Chemistry 3003-3004 | Lab of General Chemistry |
| Chemistry 3161-3013 | Bio Chemistry for the Health Sciences |
| Physic 1011 | Introductory Physics for Technicians |
| Chemistry 4205 | Photochemistry |
| PREH 4701 | Mathematical Methods for Physical Chemistry |
| TEQU 2005 | Applied Programming for Chemists |
| Chemical Technology Introductory Chemistry for Technicians | |
RESEARCH INTERESTS
Photochemistry of aromatic ethers, Photochemistry of epoxides, Photochemistry of aromatic amines, Laser Flash photolysis, Photosynthesis of amino-epoxy-polymers, Quantum Chemical calculations of spectral parameters, Quantum Chemical calculations of atomic parameters in the momentum space with Breit-Pauli-type hamiltonians, Laser Spectroscopy, Laser Photomedicine, Steady State and Lifetime Fluorescence
SUPERVISORY EXPERIENCE
Supervision of the research efforts of two undergraduate students at the TH-"Carl Schorlemmer" (1980-1981) and two undergraduate students at University of Puerto Rico at Humacao (1986-1990)
Supervision of a 6 member research group at UPR-Humacao as part of an NIH-MBRS proposal (1994-present)
AWARDED GRANTS
Photoproduction of amino-epoxy-polymers. Resource Center for Science and Engineering. UPR (1984) $5,000
Quantum chemical calculations on aromatic amines. Dean of Studies HUC (1985) $3,800Photoproduction of amino-epoxy-polymers. Resource center for Science and Engineering. UPR (1985) $5,000
Atomic energies calculations in the momentum space (In collaboration with Dr. R. Baretty, Department of Physics, Humacao University College) Dean of Studies HUC (1987) $5,000
Phototoxicity of some phenothiazine drugs studied in vitro with Nd-YAG Lasers (under the supervision of Prof. Dr. Irene E. Kochevar, Harvard Medical School; NIH (1990 -1993) $180,000
Synthesis and Laser Flash Photolysis of novel promazine derivatives; NIH - MBRS (1984-1988) $260,000
MBRS Supplemental proposal for the acquisition of a SPEX fluorolog Tau2 spectrofluorimeter (1996) $110,000
MBRS administrative supplemental proposal for the acquisition of a preparative HPLC system (1996) $22,000
Photophysical and Photochemical Properties of Neuroleptic Drugs; NIH-MBRS (1999-2002) $367,000
PUBLICATIONS
"Photochemische Untersuchungen an Epoxidharz- Modellverbindungen"; H.-J. Timpe, C. García, M. Fedtke; Z. Chem. 21, 38 (1981)
"Modelluntersuchungen zur Lichtstabilität von Epoxidharzen"; H.-J. Timpe, C. García, M. Fedtke; 7. Hochpolymerentagung Leipzig, DDR (1981)
"Photochemische Untesuchungen an Expoxidharz-Modellverbindungen"; Ph. D. Thesis THLM - "Carl Schorlemmer" DDR (1982)
"Ein neues Darstellungsverfahren für o-Hydroxy-propiophenone durch Reaktion von o-Allyl-phenolen mit Perbensoesäure"; H.-J. Timpe, C. García, E. Kunstermann; Z. Chem. 23, 52 (1983)
"Abhängigkeit der Quantenausbeute von molekularen Parametern bei der Photo-Claisen-Umlagerung aromatischer Ether"; H.-J. Timpe, C. García, H. Bögel, E. Bauwe; Z. Physik. Chem. (Leipzig) 264(2), 329 (1983)
"Photochemical and Photophysical Investigations on Bisphenol-A-Epichlorohydrin condensation polymers and Model compounds"; H.-J. Timpe, C. García, S. P. Pappas, L. R. Breskman, R. M. Fischer; Polymer Photochem. 6, 41 (1985)
"Photochemische Addition von Phenolen an Phenylglycid-ether"; H.-J. Timpe, C. García, M. Fedtke; Z. Chem., 24(5), 186 (1984)
"Photochemische Reaktionen von Arylglycidethern"; H.-J. Timpe, C. García, M. Fedtke; J. Prakt. Chem., 327(4), 616 (1985)
"Modified Breit-Pauli hamiltonian suitable for variational calculations"; R. Barrety, C. García; Int. J. Quantum Chem. 22, 425 (1988)
"Atomic energies calculations with a one-parameter integral method"; R. Barrety, C. García; J. Chem. Educ. 66(1), 45 (1989)
"Mechanism and solvent dependence for photoionization of promazine and chlorpromazine"; C. García, G. A. Smith, W. G. McGymsey, R. Redmond, I. E. Kochevar; J. Am. Chem. Soc. 117(44), 10871-10878 (1995)
"Photophysical properties of gilvocalcins V and M and their binding to calf thymus DNA"; R. Oyola, R. Arce, A. E. Alegría, C. García; Photochem. Photobiol. 65, 802-810 (1997)
"Photoaddition to DNA by Nonintercalated chlorpromazine molecules"; I.E. Kochevar, C. García and N. Geacintov; Photochem. Photobiol. 68 692-697 (1998)
"Electrochemical and Electron Spin Resonance Studies of Selected Benzazolo[3,2-a]quinolinium Salts"; O. Cox, J. A. Dumas, L. A. Rivera, C. García and A. E. Alegría (1999); J. Heteroc. Chem. (in print)
"Intramolecular Hydrogen Bonding in Hydroxylated Semiquinones Inhibit Semiquinone-Mg2+ Complex Formation"; Alegría, C. García, G. Santiago, G. Collazo and J. Morant; Biochem. Biophys. Acta, Submitted
"Photophysical, Electrochemical, and Theorical Study of Protriptyline in Several Solvents". Carmelo García, Rolando Oyola, Luis E. Piñero, Nadya Cruz, Felix Alejandro, Rafael Arce and Ileana Nieves. J Phys Chem B 2002, 106, 9794-9801.
"Photophysical and Photochemical properties of amitriptyline and nortriptyline hydrochloride: a 266 nm nanosecond laser flash and theorical study" Rafael Arce, Carmelo García, Rolando Oyola, Luis E. Piñero, Ileana Nieves, Nadya Cruz. J of Photochemistry and Photobiology A: Chemistry 154 (2003) 245-257.
PRESENTATIONS
C. García, R. W. Redmond, I. E. Kochevar; Structure-Activity analysis of the photochemistry of phenothiazine drugs; Third Pan-American Chemical Congress; San Juan, PR (SEP-1995)
C. García, J. Suárez, S. Amaro, D. Maralet, P. Lugo-Mas; Synthesis of Novel Promazine Derivatives; 19th ACS - Senior Technical Meeting, Lajas, PR (NOV-1995)
C. García, I. E. Kochevar; Fluorescence determination of binding constants for guest- host systems with two different types of complexes; 212th ACS National Meeting; Orlando, Florida (AUG-1996)
S. A. Bargouthi, K. Lawler, C. García; Spectrophotometric studies of catacondensed aromatic hydrocarbons; 212th ACS National Meeting; Orlando, Florida (AUG-1996)
C. García, J. Suárez, S. Amaro, D. Maralet, P. Lugo-Mas; Synthesis of Novel Promazine Drugs; NIGMS - Research Symposium; Washington, DC (1995)
L. Piñero, C. García, J. Suárez; Síntesis de bifenil-aminas meta substituidas; 31th. ACS Junior Technical Meeting; UPR-Arecibo, PR (MAR-1996)
P. Lugo-Mas, E. Salas, C. García, J. Suárez; Síntesis de Derivados de Promazina I; 31th. ACS Junior Technical Meeting; UPR-Arecibo, PR (MAR-1996)
S. Amaro, E. Román, C. García, J. Suárez; Síntesis de Derivados de Promazina II; 31th. ACS Junior Technical Meeting; UPR-Arecibo, PR (MAR-1996)
C. García, J. Suárez, L. Piñero, D. Maralet, P. Lugo-Mas, S. Amaro; Synthesis of Novel Promazine Derivative: Thionation vs The Smiles’ Rearrangement; 212th ACS National Meeting; Orlando, Florida (AUG-1996)
C. García, L. E. Piñero, C. Mateo, D. Maralet; Steric Effects on the Synthesis of Promazine Derivatives; 213th ACS National Meeting, San Francisco, CA (APR-1997)
Y. Abreu, C. García and L. E. Piñero; Steric Control of the Formation of Phenothiazines; NIGMS - National Minority Programs Symposium; New Orleans, Louisiana (OCT-1997)
P. Lugo-Mas, C. García, L.E. Piñero, S. Amaro, A. Morales; Geometry Control of the Formation of Promazines by Thionation; The 5th Chemical Congress of North America; Cancún, MX (NOV-1997)
J. García, C. García, L. Piñero; Geometry Control of the Smiles Phenothiazine Synthesis; The Fifth Chemical Congress of North America , Cancún Mexico (NOV-1997)
R. Oyola, R. Arce, C. García; Photophysical Properties of Phenothiazine Derivatives, The Fifth Chemical Congress of North America , Cancún Mexico (NOV-1997)
C. García; Photophysics of Promazine Drugs; MOVA Pharmaceutical Industry, Caguas PR, ACS-Chemistry Week (NOV-1997)
Yamilka Abreu, Lisandra Negrón, Luis E. Piñero, Angel Morales and Carmelo García; New Method to Synthesize Promazine Derivatives: Bioactive Molecules in the Treatment of Psychiatric Illness; ACS national Meeting; Anaheim, CA (MAR-1999)
Luis E. Piñero y Carmelo García; Control Cinético En La Síntesis De Fenotiazinas; XXIII Congreso FLAQ Rio Grande, Puerto Rico (JUL-1998)
Piñero Luis E., Morales Angel, Negrón Lisandra, Abreu Yamilka and García Carmelo; New Method to Synthesize Promazine Derivatives: Bioactive Molecules in the Treatment of Psychiatric Illness; The 1998 National Minority Research Symposium New York, New York (NOV-1998)
Yamilka Abreu, Carmelo García, Luis E. Piñero Y Angel Morales; Control Estérico En La Formación de Fenotiazinas; 33rd ACS Junior Technical Meeting; Bayamón, Puerto Rico (MAR-1998)
Ángel Morales, Yamilka Abreu, Lisandra Negrón, Luis E. Piñero y Carmelo García; Síntesis De Fenotiazinas Por Inserción De Nitrenos; 34th ACS Junior Technical Meeting and 19th Puerto Rico Interdisciplinary Scientific Meeting; Mayaguez, Puerto Rico (MAR-1999)
Carmelo García, Luis E. Piñero and Angel Morales; Photosynthesis of Promazines: Bioactive Molecules in the Treatment of Psychiatric Illness, XIX International IUPAC Photochemistry Conference; Durham, NC (AUG-1999)